Plasma Donation Appointments: What to Expect and How to Prepare

Two kinds of plasma collection

Plasma is collected by nonprofit blood services, such as the American Red Cross, and by commercial plasma centers, which may pay donors. Each sets its own eligibility rules, donation frequency and appointment system within federal regulations. Check the specific organization’s website before you book; this guide uses Red Cross information only as an example.

How plasma donation works

The Red Cross describes plasma donation this way: blood is drawn from one arm, the plasma is separated by a machine, and your red cells and platelets are returned to you along with some saline. Because of that process, a plasma visit takes longer than a whole-blood donation. The Red Cross lists the average plasma visit at about one hour and 15 minutes.

Eligibility: check before you go

Eligibility rules cover age, weight, health, medicines, travel and more, and they differ between organizations and change over time. The Red Cross, for example, collects plasma through a program for donors with type AB blood, and lists minimum age and weight requirements on its eligibility pages; it notes that final eligibility is decided at the time of donation. Read the current requirements for the organization you plan to visit.

Booking

Most organizations take appointments online or through an app, and some accept walk-ins. First-time donors may need a longer first visit for screening. Choose a time when you have eaten and are not rushed.

Preparing

General preparation advice from blood collection organizations includes:

• Eat a healthy meal beforehand and drink plenty of fluids.
• Bring a photo ID and any donor card or app login.
• Wear a top with sleeves that roll up easily.
• Bring a list of your medicines; some affect eligibility.

Follow the specific preparation instructions your center gives you.

After donating

Follow the staff’s aftercare advice, rest if you feel lightheaded, and drink fluids. The Red Cross says donors in its plasma program can give every 28 days, up to 13 times a year; other organizations set their own intervals.